Santiago to Panamá City
Traveling by bus from Santa Catalina, it is always necessary to travel first to Soná. From there, most travelers take a second bus into Santiago, a farm industry town that is at the highway crossroads. (A rest stop on the Pan American Highway acts as the mid-way stopping point for busses between Panamá City and David.) This is what I did. As Santiago is a bus hub and cross road, here is info about it.